Protein-protein interactions: better by the dozen
نویسندگان
چکیده
منابع مشابه
Discovering Domains Mediating Protein Interactions
Background: Protein-protein interactions do not provide any direct information regarding the domains within the proteins that mediate the interactions. The majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. Most of the former studies focus only on interacting domain pairs. However they do not consider the in...
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v CHAPTER 1 : GENERAL INTRODUCTION 1 Thesis Organization 5 References 9 CHAPTER 2: DISTINCTIONS MADE IN THE PROTEIN RECOGNITION OF CARBOHYDRATES 14 Abstract 14 Introduction 15 Discussion 19 Conclusion 24 References 26 CHAPTER 3: SPECIFIC EMPIRICAL FREE ENERGY FUNCTION FOR AUTOMATED DOCKING OF CARBOHYDRATES TO PROTEINS 34 Abstract 34 Introduction 35 Methods 37 Results and Discussion 42 Conclusio...
متن کاملdiscovering domains mediating protein interactions
background: protein-protein interactions do not provide any direct information regarding the domains within the proteins that mediate the interactions. the majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. most of the former studies focus only on interacting domain pairs. however they do not consider the interaction...
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متن کاملConfirming protein-protein interactions by text mining
Motivation: Although manual curation of proteinprotein interactions from literature resulted in several large databases, many interactions are still available only in manuscripts. Though PubMed does include a search engine, protein-protein interactions remain difficult to find in an automated manner. Results: OPHID Text Miner (OTM) is an information extraction system dedicated to finding specif...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2007
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth0507-389